Medical Research
(H122)
IRS Verified
DX Registered
990 on File
THE PROGERIA RESEARCH FOUNDATION INC
Financial strength (30%)
83/100
Reliability (20%)
70/100
Effectiveness (25%)
71/100
Impact (25%)
No data yet
CharityAI™ Score
Not yet evaluated
Mission Statement
The Progeria Research Foundation’s (PRF) mission is to find treatments and the cure for Progeria and its aging-related disorders. Progeria is a fatal, “rapid aging” disease that afflicts children, who die of heart disease at an average age of 13 years. PRF was founded in 1999 in response to the complete lack of resources and research on Progeria, and is the only organization in the world solely dedicated to discovering treatments and the cure for this devastating condition.
Financial Overview — FY 2025
$4.5M
Total Revenue
$4.2M
Total Expenses
$49.5M
Net Assets
15
Employees
Revenue Sources
Expense Breakdown
Program Expense Ratio
72.7%
Fundraising Efficiency
1015.5%
Operating Reserve
142.53x
Liability-to-Asset
1.1%
Revenue Diversification
54.6%
Executive Compensation
$608K
Compared with Peers
FY 2025
Compared with 162 similar organizations
(United States, Medical Research, $1M–$10M in expenses), FY 2025.
This organization
Middle half of peers (P25–P75)
Peer median
| Ratio | This org | Peer median | Position (P10 → P90) | |
|---|---|---|---|---|
|
Program expense ratio
Program expenses / total expenses
· higher is better
|
72.7% | 83.4% |
P10P90
|
Bottom quarter |
|
Admin expense ratio
Management and general / total expenses
· lower is better
|
22.4% | 10.4% |
P10P90
|
Bottom quarter |
|
Fundraising expense ratio
Fundraising expenses / total expenses
· lower is better
|
5.0% | 2.9% |
P10P90
|
Below median |
|
Fundraising efficiency
Fundraising expenses / gross fundraising income
· lower is better
|
1015.5% | 159.3% |
P10P90
|
Bottom quarter |
|
Operating reserve
Months of expenses covered by net assets
· higher is better
|
142.5 mo | 13.3 mo |
P10P90
|
Top quarter |
|
Liabilities to assets
Total liabilities / total assets
· lower is better
|
1.1% | 13.2% |
P10P90
|
Top quarter |
|
Revenue concentration
Share of revenue from the largest source
· lower is better
|
54.6% | 90.6% |
P10P90
|
Top quarter |
|
Revenue growth
Year over year revenue growth
|
22.1% | 7.8% |
P10P90
|
|
|
Expense growth
Year over year expense growth
|
-29.5% | 3.2% |
P10P90
|
|
|
Surplus margin
Surplus as a share of revenue
|
6.6% | 4.6% |
P10P90
|
Financial History
| Year | Revenue | Expenses | Net Assets | Program % | Staff |
|---|---|---|---|---|---|
| 2025 | $4.5M | $4.2M | $49.5M | 72.7% | 15 |
| 2024 | $3.7M | $5.9M | $47.4M | 82.0% | 19 |
| 2023 | $2.2M | $3.9M | $48.3M | 73.1% | 16 |
| 2022 | $1.8M | $3.1M | $46.8M | 74.5% | 15 |
| 2021 | $49.2M | $3.2M | N/A | — | 14 |
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