Medical Research (H80) IRS Verified DX Registered 990 on File

ALS THERAPY DEVELOPMENT FOUNDATION INC

EIN: 04-3462719 · WATERTOWN, MA 02472-2805 · United States · FY 2025 Data

3 out of 5 57 / 100 Based on 2+ years of filings

Financial strength (30%) 79/100

Reliability (20%) 55/100

Effectiveness (25%) 88/100

Impact (25%) No data yet

Financial data: FY 2025 · Scored 9/13/2026

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CharityAI™ Score

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Mission Statement

Founded by the ALS community and fueled by your support – the ALS Therapy Development Institute (ALS TDI) is the world's largest drug discovery lab focused solely on ending ALS

Financial Overview — FY 2025

N/A

Total Revenue

N/A

Total Expenses

N/A

Net Assets

Employees

Program Expense Ratio N/A

Fundraising Efficiency 0.0%

Operating Reserve N/A

Liability-to-Asset 0.0%

Revenue Diversification N/A

Compared with Peers

FY 2025

Compared with 35 similar organizations (United States, Medical Research, $10M–$100M in expenses), FY 2025.

This organization Middle half of peers (P25–P75) Peer median

Ratio	This org	Peer median	Position (P10 → P90)
Fundraising efficiency Fundraising expenses / gross fundraising income · lower is better	0.0%	1042.4%	P10P90	Top quarter
Liabilities to assets Total liabilities / total assets · lower is better	0.0%	22.9%	P10P90	Top quarter
Revenue growth Year over year revenue growth	-100.0%	9.8%	P10P90

Financial History

Year	Revenue	Expenses	Net Assets	Program %	Staff
2025	N/A	N/A	N/A	—	51
2024	$11.3M	$0	N/A	—	50
2023	$11.6M	$11.2M	$15.0M	88.5%	63
2022	$11.4M	$9.8M	$15.2M	89.9%	59
2021	$12.4M	$9.0M	N/A	—	48

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Organization Details

EIN: 04-3462719
State: MA
City: WATERTOWN
ZIP: 02472-2805
Classification: H80
Category: Medical Research
Rating: 3★
Coverage: A
Last Updated: Aug 2026
IRS Ruling Year: 1999
Foundation Code: 15
Form 990: On File

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CharityAI™ rates charities from 0 to 100 using public filings (IRS Form 990 and the equivalent registries outside the US) together with the information the charity itself provides on DonationX. Ratings are recalculated every quarter, without human bias, and shown as stars.

Four pillars

Financial strength30%

Program expense ratio, fundraising efficiency, operating reserves, liabilities and revenue diversification, compared with similar organizations.

Reliability20%

Standing with the registry, filing history, verification and how complete the profile is.

Effectiveness25%

How much goes to programs and how consistently the organization delivers them.

Impact25%

The outcomes the charity reports on DonationX: people served, cost per service and results.

Stars

★★★★★ 80–100 ★★★★☆ 60–79 ★★★☆☆ 40–59 ★★☆☆☆ 20–39 ★☆☆☆☆ 1–19

A pillar with no data counts as zero. Without impact metrics the score is capped at 59 (three stars): only the charity can supply that data.
The coverage grade (A to D) says how much filing data the score rests on; NONE means there is not enough to rate.
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"Compared with peers" places the charity's key ratios against organizations of the same country, sector and size.

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