Medical Research (H128) IRS Verified DX Registered 990 on File

INTERNATIONAL RETT SYNDROME FOUNDATION

EIN: 31-1682518 · WEST CHESTER, OH 45246-1104 · United States · FY 2024 Data

3 out of 5 53 / 100 Based on 2+ years of filings

Financial strength (30%) 73/100

Reliability (20%) 55/100

Effectiveness (25%) 81/100

Impact (25%) No data yet

Financial data: FY 2024 · Scored 9/13/2026

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CharityAI™ Score

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Financial Overview — FY 2024

$4.8M

Total Revenue

$5.5M

Total Expenses

$5.0M

Net Assets

Employees

Revenue Sources

Expense Breakdown

Program Expense Ratio 86.1%

Fundraising Efficiency 62.0%

Operating Reserve 10.82x

Liability-to-Asset 6.4%

Revenue Diversification 79.1%

Executive Compensation $194K

Compared with Peers

FY 2024

Compared with 332 similar organizations (United States, Medical Research, $1M–$10M in expenses), FY 2024.

This organization Middle half of peers (P25–P75) Peer median

Ratio	This org	Peer median	Position (P10 → P90)
Program expense ratio Program expenses / total expenses · higher is better	86.1%	83.0%	P10P90	Above median
Admin expense ratio Management and general / total expenses · lower is better	6.2%	10.7%	P10P90	Top quarter
Fundraising expense ratio Fundraising expenses / total expenses · lower is better	7.7%	2.0%	P10P90	Below median
Fundraising efficiency Fundraising expenses / gross fundraising income · lower is better	62.0%	97.3%	P10P90	Above median
Operating reserve Months of expenses covered by net assets · higher is better	10.8 mo	12.8 mo	P10P90	Below median
Liabilities to assets Total liabilities / total assets · lower is better	6.4%	10.1%	P10P90	Above median
Revenue concentration Share of revenue from the largest source · lower is better	79.1%	90.7%	P10P90	Above median
Revenue growth Year over year revenue growth	-0.9%	12.5%	P10P90
Expense growth Year over year expense growth	48.5%	11.1%	P10P90
Surplus margin Surplus as a share of revenue	-14.9%	2.9%	P10P90

Financial History

Year	Revenue	Expenses	Net Assets	Program %	Staff
2024	$4.8M	$5.5M	$5.0M	86.1%	16
2023	$4.9M	$3.7M	$5.9M	82.6%	14
2022	$3.7M	$5.5M	$4.5M	84.7%	14
2021	$4.1M	$4.1M	N/A	—	10

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Organization Details

EIN: 31-1682518
State: OH
City: WEST CHESTER
ZIP: 45246-1104
Classification: H128
Category: Medical Research
Rating: 3★
Coverage: A
Last Updated: Aug 2026
Foundation Code: 15
Form 990: On File

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CharityAI™ rates charities from 0 to 100 using public filings (IRS Form 990 and the equivalent registries outside the US) together with the information the charity itself provides on DonationX. Ratings are recalculated every quarter, without human bias, and shown as stars.

Four pillars

Financial strength30%

Program expense ratio, fundraising efficiency, operating reserves, liabilities and revenue diversification, compared with similar organizations.

Reliability20%

Standing with the registry, filing history, verification and how complete the profile is.

Effectiveness25%

How much goes to programs and how consistently the organization delivers them.

Impact25%

The outcomes the charity reports on DonationX: people served, cost per service and results.

Stars

★★★★★ 80–100 ★★★★☆ 60–79 ★★★☆☆ 40–59 ★★☆☆☆ 20–39 ★☆☆☆☆ 1–19

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The coverage grade (A to D) says how much filing data the score rests on; NONE means there is not enough to rate.
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