Diseases & Disorders (G80) IRS Verified DX Registered

INSPIRE HOPE FOUNDATION FOR UREA CYCLE DISORDERS INC

EIN: 45-4042399 · BRAINTREE, MA 02184-7715 · United States

1 out of 5 16 / 100 Based on summary figures only

Financial strength (30%) No data yet

Reliability (20%) 30/100

Effectiveness (25%) 38/100

Impact (25%) No data yet

Scored 9/13/2026

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Mission Statement

The Inspire Hope Foundation for Urea Cycle Disorders, Inc. is a non-profit organization which was founded in honor of our daughter, Sophia, who was diagnosed with a Urea Cycle Disorder (UCD) when she was four days old. Our families worked together to create the Inspire Hope Foundation to support Sophia and the community of other children facing the challenges of living with a UCD every day. What are the goals of the Inspire Hope Foundation? To raise funds in support of the ongoing research efforts to find new medications, treatment options and a cure for urea cycle disorders. To raise awareness about urea cycle disorders. Most people do not know what a UCD is unless a family member or friend is affected. To educate individuals and medical professionals about the presenting symptoms of the disorders to prevent delayed diagnosis. A timely diagnosis can mean the difference between life and death. To support Newborn Screening awareness programs.

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Organization Details

EIN: 45-4042399
State: MA
City: BRAINTREE
ZIP: 02184-7715
Classification: G80
Category: Diseases & Disorders
Rating: 1★
Coverage: D
Last Updated: Aug 2026
IRS Ruling Year: 2011
Foundation Code: 15

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CharityAI™ rates charities from 0 to 100 using public filings (IRS Form 990 and the equivalent registries outside the US) together with the information the charity itself provides on DonationX. Ratings are recalculated every quarter, without human bias, and shown as stars.

Four pillars

Financial strength30%

Program expense ratio, fundraising efficiency, operating reserves, liabilities and revenue diversification, compared with similar organizations.

Reliability20%

Standing with the registry, filing history, verification and how complete the profile is.

Effectiveness25%

How much goes to programs and how consistently the organization delivers them.

Impact25%

The outcomes the charity reports on DonationX: people served, cost per service and results.

Stars

★★★★★ 80–100 ★★★★☆ 60–79 ★★★☆☆ 40–59 ★★☆☆☆ 20–39 ★☆☆☆☆ 1–19

A pillar with no data counts as zero. Without impact metrics the score is capped at 59 (three stars): only the charity can supply that data.
The coverage grade (A to D) says how much filing data the score rests on; NONE means there is not enough to rate.
An organization that is not in good standing with its registry (for example a revoked tax exemption) is shown as Not rated.
"Compared with peers" places the charity's key ratios against organizations of the same country, sector and size.

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