Diseases & Disorders (G80) IRS Verified DX Registered 990 on File

MITOACTION INC

EIN: 55-0899427 · BOSTON, MA 02109-5800 · United States · FY 2024 Data

3 out of 5 53 / 100 Based on 2+ years of filings

Financial strength (30%) 82/100

Reliability (20%) 55/100

Effectiveness (25%) 68/100

Impact (25%) No data yet

Financial data: FY 2024 · Scored 9/13/2026

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Mission Statement

MitoAction, a Boston-based 501(c)(3) charity incorporated in 2005 (tax ID 55-0899427), is dedicated to improving the quality of life for children, adults, and families living with mitochondrial disease through support, education, outreach, advocacy, and clinical research initiatives. Mitochondrial disease is an inherited chronic illness that can be present at birth or develop later in life. It causes debilitating physical, developmental, and mental disabilities with symptoms including poor growth; loss of muscle coordination; muscle weakness and pain; seizures; vision and/or hearing loss; gastrointestinal issues; learning disabilities; and heart, liver, or kidney failure. About 1 in 4,000 people has Mito. It’s progressive and there is no cure.

Financial Overview — FY 2024

$417K

Total Revenue

$503K

Total Expenses

$1.0M

Net Assets

Employees

Revenue Sources

Expense Breakdown

Program Expense Ratio 74.0%

Fundraising Efficiency 20.4%

Operating Reserve 24.21x

Liability-to-Asset 2.4%

Revenue Diversification 57.1%

Compared with Peers

FY 2024

Compared with 1,541 similar organizations (United States, Diseases & Disorders, $100K–$1M in expenses), FY 2024.

This organization Middle half of peers (P25–P75) Peer median

Ratio	This org	Peer median	Position (P10 → P90)
Program expense ratio Program expenses / total expenses · higher is better	74.0%	83.1%	P10P90	Below median
Admin expense ratio Management and general / total expenses · lower is better	15.4%	10.9%	P10P90	Below median
Fundraising expense ratio Fundraising expenses / total expenses · lower is better	10.6%	0.3%	P10P90	Bottom quarter
Fundraising efficiency Fundraising expenses / gross fundraising income · lower is better	20.4%	19.0%	P10P90	Below median
Operating reserve Months of expenses covered by net assets · higher is better	24.2 mo	12.0 mo	P10P90	Above median
Liabilities to assets Total liabilities / total assets · lower is better	2.4%	0.7%	P10P90	Below median
Revenue concentration Share of revenue from the largest source · lower is better	57.1%	93.9%	P10P90	Top quarter
Revenue growth Year over year revenue growth	-44.8%	7.6%	P10P90
Expense growth Year over year expense growth	-3.4%	9.1%	P10P90
Surplus margin Surplus as a share of revenue	-20.8%	1.8%	P10P90

Financial History

Year	Revenue	Expenses	Net Assets	Program %	Staff
2024	$417K	$503K	$1.0M	74.0%	2
2023	$754K	$521K	$1.1M	75.3%	4
2022	$415K	$479K	$784K	75.7%	3
2021	$398K	$403K	N/A	—	3

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Organization Details

EIN: 55-0899427
State: MA
City: BOSTON
ZIP: 02109-5800
Classification: G80
Category: Diseases & Disorders
Rating: 3★
Coverage: A
Last Updated: Aug 2026
IRS Ruling Year: 2003
Foundation Code: 15
Form 990: On File

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CharityAI™ rates charities from 0 to 100 using public filings (IRS Form 990 and the equivalent registries outside the US) together with the information the charity itself provides on DonationX. Ratings are recalculated every quarter, without human bias, and shown as stars.

Four pillars

Financial strength30%

Program expense ratio, fundraising efficiency, operating reserves, liabilities and revenue diversification, compared with similar organizations.

Reliability20%

Standing with the registry, filing history, verification and how complete the profile is.

Effectiveness25%

How much goes to programs and how consistently the organization delivers them.

Impact25%

The outcomes the charity reports on DonationX: people served, cost per service and results.

Stars

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